Biological effects of nanomaterials with a focus on toxicity should receive great attention since commercial products as well as medical tools increasingly utilize them. Especially, a fundamental understanding of nanotoxicology is highly desirable both from the material’'s stand point as well as from the biological system’'s point of view. Titanium dioxide (TiO2) is a widely used material in our life: for example, cosmetics of sun-cream to block UV radiation. However, despite its wide array of common applications, its pathogenetic role was always suggested under certain conditions. In this work, the toxicity of TiO2 nanoparicles on human skin- and lung cell was investigated using 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfo phenyl)-2H-tetrazolium (MTS) assay- and confocal microscopy for live &dead of cells. The human skin- and lung-cell were purchase from from Korean Cell Line Bank. We observed that TiO2 nanoparticles impedes the cell growth using MTS, and dead cells increase depending on the concentration of TiO2 nanoparticles using confocal microscopy. Based on the results mentioned above, we discuss the toxicity and the safety of TiO2 nanoparicles for the human cells.
키워드
TiO2Human CellToxicity
저자
Joo-Kyung LEE [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
Xio-Lung DENG [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
SeongWung KANG [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
BaeHo PARK [ Division of Quantum Phases and Devices, Konkuk University, Seoul, Korea. ]
JiYeong WON [ College of BioNano Technology, Kyungwon University, Seongnam, Korea. ]
JunHong MIN [ College of BioNano Technology, Kyungwon University, Seongnam, Korea. ]
EunGyu LEE [ College of BioNano Technology, Kyungwon University, Seongnam, Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동