Earticle

초록

영어

Surface enhanced Raman scattering (SERS) sensing has attracted considerable attention for ultrasensitive, highly specific and multiplex biomolecular assays. Here we demonstrated the SERS-active nanostructures to highly sensitive detect SERS signals. In order to fabricate the
SERS-active substrate, densely packed, 200 nm diameter, metal nanotube arrays were made using an anodized alumina nanoporous membrane as a template for shadow evaporation. The nanotubes on SERS-active PDMS substrate are well ordered with uniform packing and an average diameter of 200 nm. We explore the use of two kinds of SERS-active metal nanotube substrates: a single layer Au structure and a multilayer Au/Ag/Au structure. The latter multilayer structure was designed to in order to take advantage of the greater SERS enhancement offered by the silver while maintaining the biocompatibility and chemical reactivity characteristics (for immobilization of the capture aptamer) offered by the gold outer layer. We also demonstrate a facile assembly technique by which the metallic substrates can be integrated with an all PDMS
microfluidic chip.

키워드

저자

• Yun Suk HUH [ Division of Material Science, Korea Basic Science Institute. ]
• Aram J. CHUNG [ Sibley School of Mechanical and Aerospace Engineering, Cornell University. ]
• Hae Jin KIM [ Division of Materials Science, Korea Basic Science Institute. ]
• David ERICKSON [ Sibley School of Mechanical and Aerospace Engineering, Cornell University. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576