Earticle

초록

영어

The objective of this study was to identify the proteins involved in myogenesis and adipogenesis. Global proteins were monitored in skeletal muscle and adipose tissue between bull and steer, respectively. Through proteomic analysis and comparison, we identified 4 differentially expressed (two-fold or more) proteins from skeletal muscle in steer, down-regulated A, B, C and up-regulated D, and also identified two up-regulated proteins from adipose tissue, E and F. In vitro, after myogenic differentiation of a bovine cell line, the mRNA expression of A, B and D did not changed, but that of C increased significantly (P<0.05). After adipogenic differentiation of a bovine cell line, the mRNA expression of F did not significantly vary, but the expression of E showed about 1.7-fold increase. Therefore, we suggest that C could be indicative
of positive regulator of myogenesis, and E indicative of positive regulator of adipogenesis since they showed a differential expression before and after myogenic and adipogenic differentiation.

키워드

저자

• Qiankun ZHANG [ Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921. ]
• Hong-Gu LEE [ Dept. of Animal Science and PNU-Special Animal Biotechnology Center, Pusan National University, Gyeongnam 627-706. ]
• Jung-A HANG [ Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921. ]
• Myunggi BAIK [ Dept. of Applied Bioscience and Biotechnology, Chonnam National University, Kwangju 500-757. ]
• Yun-Jaie CHOI [ Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576