Excess ethanol intake is usually toxic in health. Chronic ethanol consumption causes oxidative damage in liver. Alcohol dehydrogenase (ADH), microsomal ethanol oxidation system (MEOS) and catalase are related with the ethanol metabolism. Classical pathway of ethanol metabolism, which is catalysed by alcohol dehydrogenase to form acetaldehyde, results in the formation of free radicals. Acetaldehyde has been known to be a major contributor to hangover. Acetaldehyde is a malignant metabolite for vasodilation substance, flushing induction, and respiratory distress induction as well as exhibiting to be intense reactive and toxic. Acetaldehyde combined with phospholipid, amino acid residues, and sulfhydryl group may transform cell surface antigen and induce lipid peroxidation and oxidant stress as well as depleting antioxidant enzyme glutathione (GSH). In this study, we investigated the effect of Acer tegmentosum MAX. extracts on relieving hangovers in rats. Male Sprague-Dawley rats were given Acer tegmentosum MAX. extracts (10ml/kg body weight) ingestion and before or after 40% Ethanol (5g/kg body weight) ingestion. The effect of Acer tegmentosum MAX. extracts on blood ethanol and acetaldehyde concentration was studied. In consequence, Acer tegmentosum MAX. extracts were recognized to reduce the blood ethanol and acetaldehyde concentration.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동