Lian Hua LUO, Jeong-Woo SEO, Dae-Hyuk KIM, Chul Ho KIM
언어
영어(ENG)
URL
https://www.earticle.net/Article/A119660
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원문정보
초록
영어
3-hydroxypropionic acid (3-HP) is expected to build up huge market in biomass derived valuable platform chemicals recently and its commercial mass production will led to bio-refinery industrial development. In glycerol metabolism of bacteria, 3-HP is generally known as converting from 3-hydroxypropionaldehyde (3-HPA) by aldehyde dehydrogenase. To find out the appropriate enzyme for achieving the effective catalysis, 32 kinds of gene encoding each of the dehydrogenase from Lactobacillus reuteri were cloned with dhaT which encoding 1,3-propandiol oxidoreductase, and expressed in Klebsiella pneumoniae AK strain (1). Among 32 recombinants, a half of them illustrated enhancement aspects comparing with the control while eight showed lower 3-HP production. The highest 3-HP production was investigated in the recombinant strain which containing a gene encoding propanediol utilization protein. The enzyme will be useful for improvement of the 3-HP production.
Lian Hua LUO [ Microbe-based Fusion Technology Research Center, Jeonbuk Branch Institute, KRIBB, Jeongeup, Jeonbuk 580-185, South Korea. ]
Jeong-Woo SEO [ Microbe-based Fusion Technology Research Center, Jeonbuk Branch Institute, KRIBB, Jeongeup, Jeonbuk 580-185, South Korea. ]
Dae-Hyuk KIM [ Institute for Molecular Biology and Genetics, Research Center of Bioactive Materials, Chonbuk National University, Jeonju, Chonbuk 561-756, South Korea. ]
Chul Ho KIM [ Microbe-based Fusion Technology Research Center, Jeonbuk Branch Institute, KRIBB, Jeongeup, Jeonbuk 580-185, South Korea. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동