Mussel adhesive proteins (MAPs), found in byssal adhesive plaques, have come to be recognized as very attractive biomaterials thanks to their fascinating thanks to their fascinating properties including strong and flexible adhesion in any substrates in wet environments. Especially, MAP fp-5 from the highest 3,4-dihydroxyphenyl-L-alanine (DOPA) content is mainly involved in binding, serving as a adhesive between a surface and the adhesion plaque of mussels. However, it has been very difficult to obtain purified natural MAP fp-5 in quantity. In this study, we firstly over-expressed Mytilus galloprovincialis-originated fp-5 in Escherichia coli and efficiently purified the protein. Mechanical properties of fp-5 was investigated, and multi-functional coatings were formed through simple dip-coating of objects in a fp-5 aqueous solution. From this study, we expect MAP fp-5 can be used as a significant bioadhesive and an efficient multi-functional surface coating material.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동