Jung-Keug PARK, Kye-Yong SONG, Hwa-Sung LEE, Young-Kwon SEO
언어
영어(ENG)
URL
https://www.earticle.net/Article/A119259
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원문정보
초록
영어
A severely injured anterior cruciate ligament (ACL) does not heal well, and can cause knee instability, meniscal damage, and osteoarthritis. Patellar tendon autografts and allografts are widely used but are not suited for an ACL reconstruction. The problems associated with an autograft include lengthy rehabilitation as well as persistent patellar pain. Allografts carry the risk of disease transmission, and their procurement is difficult and costly. Permanent synthetic ACL prostheses, including the Gore Tex prosthesis, Stryker-Dacoron ligament, and Kennedy ligament augmentation device, may show satisfactory performance in the short term but they tend to break down and fail in the long term. Recently, a tissue engineering strategy has been attempted for an ACL reconstruction. The ideal ACL replacement scaffold should be biodegradable, porous, biocompatible, show adequate mechanical strength, and be able to promote the formation of ligament tissue. Several groups have reported the potential ACL scaffold using collagen, silk, and biodegradable polymers such as polyglycolic acid (PGA) and polylactic acid (PLA). Over the past 20 years, silk and a variety of degradable synthetic materials including PGA have been used as biomedical suture materials. In addition, silk and PGA fibers were studied to regenerate tendon and ligament defects. The biocompatibility of implant materials is of major concern in orthopedic surgery. After implantation, host-material interactions occurring at the implant site can be cause adverse inflammatory reactions.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동