Insulin-secreting pancreatic islet transplantation is one of the most promising strategies for patients suffering from diabetes mellitus, but they must be eliminated by host’s immune graft rejection. To protect transplanted islets in host, bioengineered pancreatic islets are being developed. To this end, surface modification with biocompatible polymer and cellular reconstruction technology are introduced. Here PEG-based chemical immunoprotection can provide an effective therapy that protects transplanted islets at least for one year when CsA was administered. Also, when the structure of pancreatic islets was reconstructed with bio-MEMS technology, the immunity of them was attenuated without any modification or treatment of any agent. Finally, these bioengineered pancreatic islets could cure the hyperglycemia in diabetic animals. Therefore, these technologies could strongly support the successful pancreatic islet transplantation for hunting diabetes mellitus.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동