Da Mi CHOI, Jin Young KIM, Jae Hyoung AHN, Wan Hee KIM, Ji Young CHO, In Seop KIM, Jung Eun BAE, Ke Won KANG
언어
영어(ENG)
URL
https://www.earticle.net/Article/A115249
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원문정보
초록
영어
An experiment was carried out to compare wound healing processes from the porcine skinderived and human-derived wound dressings. A common treatment of wounds is wound dressing derived from human cadaver skins which were distributed by approved tissue banks. The wound dressings are processed for hospital uses under the strict guidelines. The supply of human skins is limited. Therefore, we examined possibility of an alternative source of processed wound dressing derived from porcine skin. Porcine skins were procured using Dermatome (Zimmer Inc.) and manufacturing process was followed as human cadaver skin (Hans Biomed Procedures). Final dressing and intermittent processing materials were examined to compare with human skin in physical and biochemical properties. And a beagle dog was used in vivo experiment, induced wounds and applied dressing materials from both porcine and human. Structural and physical properties of the two skin dressings were showed similar by SEM, histological analysis, IHC, tensile strength, collagenase decomposition and GAGs assay. Also in an animal experiment, wound healings were taking place about the same degree of contraction and epithelialization whether porcine or human originated materials applied. In conclusion, porcine skin-derived dressing may be found to have equivalent efficacy and effects as the human skin-derived. We suggest that wound dressing derived from porcine skin can be used, when human skinderived dressings are not available and manufactured under the proper guideline.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동