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Effect of High Pressure Extraction on Anticancer Activities of Fresh Ginseng

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2009 추계학술대회 및 국제심포지움 (2009.11)바로가기
  • 페이지
    pp.202-202
  • 저자
    Myoung Hoon JEONG, Ji Hye HA, Ling JIN, Sung Ho OH, Heon Sang JEONG, Jae Hyun JUNG, Kwang Wan YU, Hyeon Youg LEE
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A115196

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원문정보

초록

영어
The purpose of this study was to investigate the possibility of enhancing biological activities of fresh ginseng which has no commercial value. Fresh ginseng was extracted under high pressure extraction condition at 80℃ and 120 bar for 20min. On the basis of HPLC analysis, amounts of ginsenosides in fresh ginseng were increased up to 10-30% by High Pressure Extraction (HPE) process, compared to conventional water extraction at 100℃. Quantitatively, amounts of Rh1 and Rg3 which were main protopanaxatriol ginsenosides, were measured as 620.08ppm and 313.97ppm. Rh2, Rg2 and Rf which were protopanaxadiol ginsenosdies group were also increased up to 665.16ppm, 415.21ppm, and 477.34ppm, respectively. The cytotoxicity of the extracts on human normal kidney cell, HEK293 was 11.3% which was much lower than those from conventional extraction processes in adding 1.0 ㎎/㎖ of the highest concentration. Human stomach adenocarcinoma and human lung carcinoma cell growth were inhibited up
to 80% and 87%, respectively in adding 1.0 mg/ml of extracts. These values were higher 30-40% than those from water extraction at 100℃. It was found that fresh ginseng associated with high pressure extraction process could improve its anticancer activities because the extraction process could generate more active compounds of Rg1, Rg2, Rh1, Rh2, Re, Rf and Rd than those from normal extractions. Some compounds such as Rg1, Rg2, Rh1 and Rh2 were found in the extracts from high pressure process in fresh ginseng

키워드

Ginseng Hign pressur extraction Anticacner activity Ginsenosdie

저자

  • Myoung Hoon JEONG [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University. ]
  • Ji Hye HA [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University. ]
  • Ling JIN [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University. ]
  • Sung Ho OH [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University. ]
  • Heon Sang JEONG [ College of Agriculture, Life & Environment Science, Chungbuk National University ]
  • Jae Hyun JUNG [ Department fo Food and Biotechnology, Chungju National University ]
  • Kwang Wan YU [ Department fo Food and Biotechnology, Chungju National University ]
  • Hyeon Youg LEE [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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