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Enhancement of Immuno-modulatory Activities of Fresh Ginseng Associated with Ultrasonification Extraction

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2009 추계학술대회 및 국제심포지움 (2009.11)바로가기
  • 페이지
    pp.201-201
  • 저자
    Myoung Hoon JEONG, Ji Hye HA, Ling JIN, Seung Seop KIM, Heon Sang JEONG, Jae Hyun JUNG, Kwang Wan YU, Hyeon Yong LEE
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A115195

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원문정보

초록

영어
Immuno-modulatory activities of fresh ginseng could be improved by employing ultrasonification extraction process. Fresh ginseng was extracted at 60℃ with water for 60min, and then treated with ultrasonification at 40 kHz for 15min. From HPLC analysis, amounts of ginsenosides, Rb1, Rb2, Rd, Rg1, Re, and Rf were increased up to 2-3 times, compared to these from
conventional water extraction. The extracts also showed low cytotoxicity on human kidney cell (HEK293) as 15%. For human B and T cell growth, fresh ginseng extracted by ultrasonification process showed the highest cell growth as 9.33ⅹ104 cells/ml and 8.50ⅹ104 cells/ml, respectively, which were increased up to 35% compared to those from conventional extraction process. The secretion of cytokine for IL-6 and TNF-αfrom human T cell were also increased to 8.5ⅹ10-4 pg/ml and 8.3ⅹ10-4 pg/ml, respectively in adding the extracts. Based HPLC peaks comparison between crude extracts and the extracts treated with ultrasonification, ultrasonification process definitely plays an important role in effectively extracting biologically active compounds, which could result in improving immuno-modulatory activities.

키워드

Ginseng Immuno modulatory activity Ultrasonification extracion

저자

  • Myoung Hoon JEONG [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]
  • Ji Hye HA [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]
  • Ling JIN [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]
  • Seung Seop KIM [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]
  • Heon Sang JEONG [ College of Agriculture, Life & Environment Science, Chungbuk National University ]
  • Jae Hyun JUNG [ Department fo Food and Biotechnology, Chungju National University ]
  • Kwang Wan YU [ Department fo Food and Biotechnology, Chungju National University ]
  • Hyeon Yong LEE [ Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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