Myoung Hoon JEONG, Ling JIN, Ji Hye HA, Eul Kwon CHUNG, Ae Ran CHUNG, Hak Ju LEE, Ha Young KANG, Hyeon Yong LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A115190
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원문정보
초록
영어
Berberis koreana bark extracts was encapsulated with edible polymers, gelatin or chitosan. The sizes of most nano particles were in the range of 100-300 nm. The nano particle by gelatin showed relatively higher anticancer activities then chitosan nano particles. The cytotoxicity of all the nano-particles on human kidney cell (HEK293) was low as 15% at 1 mg/ml concentration, which was relativity low cytotoxicity. The growth of human lung cancer cells, human stomach cancer cells, human breast cancer cell, human liver cancer cells and human colonicnic carcinoma cancer cells were inhibited as 74.5%, 79.8%, 86,6%, 68.4%, and 80.7% respectively. These inhibition ratios were generally higher than those from crude extracts of Berberis koreana bark. The selectivity was also higher than that of crude extracts. It was found that nano-encapsulation of the extracts crude improve their biological activities possibility due to effective delivery systems.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동