Jung Im LEE, You Ah KIM, Chang-Suk KONG, Jinhyeok LEE, Haejin KIM, Youngwan SEO
언어
영어(ENG)
URL
https://www.earticle.net/Article/A115144
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원문정보
초록
영어
The scavenging activity of Magnolia denudata Desrousseaux on reactive oxygen species (ROS) were evaluated using 2’,7’-dichlorofluorescin diacetate (DCFH-DA) in HT 1080 cells. Methanol (MeOH) and dichloromethane (CH2Cl2) extracts inhibited dose-dependently generation of ROS in the cellular system. MeOH and CH2Cl2 extracts were combined and fractionated with n-hexane, 85% aqueous MeOH, and n-butanol (n-BuOH). Both n-hexane-soluble and 85% aqueous-soluble fractions showing strong radical-scavenging activity in the cellular system were further separated by diverse chromatographic methods to give five known lignans. All these compounds exhibited significant radical-scavenging effect on intracellular ROS in a dose-dependent manner. Their scavenging activity on various reactive oxygen species (ROS) was also evaluated using electron spin resonance (ESR) spintrap techniques.
키워드
Magnolia denudata DesrousseauxROSESR
저자
Jung Im LEE [ Division of Marine Environment & Bioscience, Korea Maritime University ]
You Ah KIM [ Division of Marine Environment & Bioscience, Korea Maritime University ]
Chang-Suk KONG [ Marine Bioprocess Research Center, Pukyong National University ]
Jinhyeok LEE [ Division of Marine Environment & Bioscience, Korea Maritime University ]
Haejin KIM [ Division of Marine Environment & Bioscience, Korea Maritime University ]
Youngwan SEO [ Division of Marine Environment & Bioscience, Korea Maritime University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동