Mannheimia succiniciproducens MBEL55E is a capnophilic gramnegative bacterium which efficiently produces succinic acid. In order to analyze metabolic pathways of M. succiniciproducens, we applied pathway analysis to the biochemical network of M. succiniciproducens, previously developed by our group. We then also analyzed the biochemical network of Escherichia coli, in the same way as above, in order to grasp the notable differences between these two organisms. We clustered the solutions of two microorganisms, and compared each other. Each of clusters showed characteristic yield of succinic acid and the number of solutions and clusters of M. succiniciproducens is greater than that of E.coli. [This work was supported by the Genome-based Integrated Bioprocess Project of the Ministry of Education, Science and Technology (No. 2005-01294). Further supports by the LG Chem Chair Professorship, Microsoft, IBM SUR, WCU(World Class University) program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (R32-2008-000-10142-0) are appreciated.]
Sang Yup LEE [ Department of Chemical and Biomolecular Engineering (BK21 Program), Metabolic and Biomolecular Engineering National Research Laboratory, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701. ]
Tae Yong KIM [ Department of Chemical and Biomolecular Engineering (BK21 Program), Metabolic and Biomolecular Engineering National Research Laboratory, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701. ]
Hyung Rok CHOI [ Department of Chemical and Biomolecular Engineering (BK21 Program), Metabolic and Biomolecular Engineering National Research Laboratory, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon 305-701. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
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