Seong-Eon PARK, Jeong-Eun LEE, Yong-Cheol PARK, Jin-Ho SEO
언어
영어(ENG)
URL
https://www.earticle.net/Article/A115097
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Bioethanol is the most common renewable fuel today. During pretreatment processes for cellulosic biomass, furan-derived inhibitors such as furfural and hydroxymethylfurfural(HMF) which decrease ethanol productivity are generated. The conversion rate of furfural and HMF is a key factor for obtaining a high fermentation performance. Enzymes which supply cofactors, or those which convert furfural and HMF to less toxic compounds were chosen as candidate targets. Aldehyde dehydrogenase 6 (ALD6) is involved in supplying a cofactor, NADPH, which is needed for reduction of furfural and HMF. In addition, the specific rate of furfural oxidation was increased by 2.2-fold higher, and that of HMF oxidation by 2.5-fold higher in the ALD6 overexpressed strain compared to the control strain. Furthermore, ethanol productivity of the ALD6 overexpressed strain in fermentations with media containing both furfural and HMF increased by 33.2 % compared to the control strain. Consequently, the tolerant properties of S. cerevisiae against furan-derived inhibitors were improved by overproduction of ALD6.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동