In butyric acid fermentation, a high concentration of butyric acid is a key factor which makes the recovery of the product economically. However, toxic effects of acids prevent the cell from producing ca. 50 g/L in batch or fed-batch process. To solve this problem, several insitu recovery processes have been developed. Ion-exchanger and adsorbent are able to remove organic acids which reduce their toxic effects in a fermentor, but low adsorption capacity together with the inhibitory effects on the cell growth when using large amount of ionexchanger must be addressed. In our research, new inhibition mechanism by adsorbent was found for anaerobic fermentation. Iron and manganese are key components for anaerobic respiration. The addition of adsorbent removed these components resulting in the decrease in fermentation productivity. To prevent and alleviate the inhibition effect, small amount of these minerals were added after butyric acid adsorption. This addition was able to recover the productivity after adsorption process which resulted in the increase of 20% in overall productivity compared to that in the culture in the absence of adsorbent.
키워드
butyric acidfermentationadsorbentmineralmechanism
저자
Jae Yeon PARK [ Center for Environmental Research Center, Energy and Environment Research Division, Korea Institute of Science and Technology ]
Youngsoon UM [ Center for Environmental Research Center, Energy and Environment Research Division, Korea Institute of Science and Technology ]
Byoung-In SANG [ Center for Environmental Research Center, Energy and Environment Research Division, Korea Institute of Science and Technology ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
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