Earticle

초록

영어

4 kinds of RNPs(Regional Special Natural Products) were used to verify for Anti-obesity effet. In the western blot for 3T3-L1 cell, expression level of PPARγ(peroxisome proliferator-activated receptor γ) was suppressed by different concentraton of 4 RNPs when treated chemical with MDI(IBMX, Dexamethasone, Insulin) at the same time. Also, SREBP-1(Sterol regulatory element binding protein) and PPARγ expression levels were reduced by 4 RNPs in a dose-dependent manner when treated chemicals after differentiation. And adipogenesis was reduced by 7.5%, 14.4%, 18.3% and 30% at different concentration of Anthrisci Radix when performed Oil red O staining. Also, it was reduced by 2%, 4.9%, 9.3% and 38% at different concentration of Psoraleae Semen. When treated with Siegesbeckiae Herba, it was inhibited by 1.4%, 6.4%, 16.4% and
30.1%, respectively. And Corni Fructus was also showed by 0.9%, 6.3%, 13.7% and 33% at same concentration of Siegesbeckiae Herba. As a result, 4 RNPs were expected for a useful material for Anti-obesity and Anti-cancer as well.

키워드

저자

• Jong Deog KIM [ Department of Biotechnology, Research center on Anti-Obesity and Health Care, Chonnam National University ]
• Jin Hyuk SHIN [ Department of Biotechnology ]
• Gu Yong CHA [ Dept. of Culture Biotechnology ]
• Kyeong Wan KANG [ Dept. of Culture Biotechnology ]
• Go Un CHAE [ Department of Biotechnology ]
• Jong Hoon LEE [ Department of Biotechnology ]
• Jae Ho HWANG [ Dept. of Culture Biotechnology ]
• Hyo Jin SEO [ Department of Biotechnology ]
• Tai Sun SHIN [ Food Science and Nutrition, Research center on Anti-Obesity and Health Care, Chonnam National University ]
• Kyeong Ho HAN [ Dept. of Culture Biotechnology ]
• Min Yong KIM [ Dept. of Refrigeration Eng., Chonnam National University, Research center on Anti-Obesity and Health Care, Chonnam National University ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576