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산업원천기술개발사업 성과발표회 : 좌장: 김승욱 교수(고려대학교)

Development of The New Herbicide MRC-01

첫 페이지 보기
  • 발행기관
    한국생물공학회 바로가기
  • 간행물
    한국생물공학회 학술대회 바로가기
  • 통권
    2009 추계학술대회 및 국제심포지움 (2009.11)바로가기
  • 페이지
    pp.113-113
  • 저자
    Suk-Jin Koo, Ki-Hwan Hwang, Man-Seok Jeon, Sung-Hun Kim, Jongsoo Lim, Dong-Guk Lee, Keun-Hoe Chung, Young-Kwan Ko, Jae-Wook Ryu, Dong-Wan Koo
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A114483

※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

원문정보

초록

영어
MRC-01 (common name: methiozolin), 5-(2,6-difluoro-benzyloxymethyl)-5-methyl-3-(3-methyl- thiophen-2-yl)-4,5-dihydro-isoxazole, is a new herbicide candidate. This compound belongs to isoxazoline family, but not related to any other commercialized pesticides. MRC-01 has safety to various crops including soybean, wheat, rice, cotton, and turfgrass, and controls certain grass weeds such as barnyardgrass (Echinochloa crusgalli), crabgrass (Digitaria sp.), annual bluegrass (Poa annua), blackgrass (Alopecurus myosuroides) etc by pre or post-emergence application at 250 to 1,000 g/ha. In turf, MRC-01 has a high safety to various cool season turf species including bentgrass and Kentucky bluegrass, and controls the major grass weeds (annual bluegrass and crabgrass). MRC-01 is superior to the commercial standards in post emergence activity. MRC-01 mode of action was shown, by [14C]-glucose incorporation study, to be a strong inhibitory activity in cell wall biosynthesis in maize. Toxicology studies have proven that MRC-01 has a high safety to mammals, fishes, bees, earthworm, and birds etc. The molecule was non-genotoxic and nonteratogenic. Animal metabolism study showed that MRC-01 was readily absorbed in the gastrointestinal tract, rapidly metabolized in the liver, and excreted through bile, faces, and urine. Greater than 90% of the administered was excreted out within 96 h. In rats, numerous minor metabolites were formed and one of the metabolites was identified to be 2-(5-((2,6- difluorobenzyloxy)methyl)-4,5-dihydro-5- methylisoxazol-3-yl)thiophen-3-yl)methanol. In soil, MRC-01 was readily degraded in a non-sterile aerobic condition. In field dissipation studies, DT50 of MRC-01 was about 10 days. Collectively, MRC-01 has a unique fitness as a turf herbicide and favorable toxicology and environmental fate. MRC-01 was applied for registration for turf uses in September 2009 to KRDA, and is in registration trials in Japan.

저자

  • Suk-Jin Koo [ Moghu Research Center Ltd. ]
  • Ki-Hwan Hwang [ Moghu Research Center Ltd. ]
  • Man-Seok Jeon [ Moghu Research Center Ltd. ]
  • Sung-Hun Kim [ Moghu Research Center Ltd. ]
  • Jongsoo Lim [ Moghu Research Center Ltd. ]
  • Dong-Guk Lee [ Moghu Research Center Ltd. ]
  • Keun-Hoe Chung [ Moghu Research Center Ltd. ]
  • Young-Kwan Ko [ Korea Research Institute of Chemical Technology ]
  • Jae-Wook Ryu [ Korea Research Institute of Chemical Technology ]
  • Dong-Wan Koo [ Korea Research Institute of Chemical Technology ]

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
  • 설립연도
    1984
  • 분야
    공학>생물공학
  • 소개
    이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동

간행물

  • 간행물명
    한국생물공학회 학술대회
  • 간기
    반년간
  • 수록기간
    1985~2013
  • 십진분류
    KDC 476 DDC 576

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