Earticle

초록

영어

The specificity of enzymes promises great improvements in a variety of their potential applications. However, the short lifetimes of enzymes frequently limit their usefulness. Recent breakthroughs in nanotechnology have made various nanostructured materials more affordable for a broader range of applications, including enzyme immobilization and stabilization [1-3]. This presentation will discuss recent developments in nanobiocatalysis to improve the enzyme stability using various nanostructures such as single enzyme nanoparticles (SENs), mesoporous
materials, nanofibers, nanoparticles, and carbon nanotubes. In the form of SENs, each enzyme molecule is surrounded with a nanometer scale network, resulting in stabilization of enzyme activity without any serious limitation for the substrate transfer from solution to the active
site [4]. The approach of nanometer-scale enzyme reactors (NERs) stabilized enzymes in mesoporous media via a ship-in-a-bottle effect, which employs adsorption of enzymes followed by enzyme crosslinking [5]. A similar approach resulted in the enzyme coating on the surface
of electrospun nanofibers, which also stabilized the enzyme activity in a vivid way [6-7]. Stabilized enzyme systems in various nanostructures will make an ideal system for many applications including bioremediation, antifouling, biosensors, bioreactors, microfluidic devices, trypsin digestion, and biofuel cells. Several successful examples of nanobiocatalytic
applications will be given in this presentation.

저자

• Jungbae Kim [ Korea University, Department of Chemical & Biological Engineering ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576