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한국생명공학연구원 성과발표회 : 공동개최: 한국생명공학연구원 : 좌장: 홍순광 교수(명지대학교)
Biological production of 1,3-propanediol and 3-hydroxypropionic acid from glycerol
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- 발행기관
- 한국생물공학회 바로가기
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- 간행물
- 한국생물공학회 학술대회 바로가기
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- 통권
- 2009 추계학술대회 및 국제심포지움 (2009.11)바로가기
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- 페이지
- pp.84-84
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- 저자
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- 언어
- 영어(ENG)
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- URL
- https://www.earticle.net/Article/A114441
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
- 영어
- Currently, a bulk amount of raw glycerol is formed as the main by-product during biodiesel production, which is as high as 10% (w/w) of biodiesel generated. The surplus of raw glycerol has not only greatly disturbed the market of traditional glycerol in the preparation and price, but also brought a significant environmental problem since it cannot be discharged direct into the environment without any treatment. As a result of these issues, a large research effort has been devoted to developing methods to refine glycerol as a low-cost feedstock into industrially
valuable materials such as fuels, building blocks, and bioactive substances. 1,3-Propanediol (1,3-PD) is a valuable chemical that is used mainly for the synthesis of polymethylene terephalates by polymerization with terephthalates. Use of this polymer in the manufacturing of textile fiber, film, plastic, etc. is rapidly expanding. Klebsiella pneumoniae is a typical microbial strain capable of producing 1,3-PD, in which the metabolic pathway responsible for the production of 1,3-PD has been well studied. The microbial production of 1,3-PD by K. pneumoniae involves the formation of various by-products. 2,3-Butanediol, one of the main by-products, may serve as an obstacle for obtaining a high purity of 1,3-PD in downstream processes because of its similar boiling point. To eliminate the by-products synthesis, glycerol
metabolic pathway was engineered by deleting from the chromosomal DNA the genes involved in the synthesis of by-products. The by-product formation except for acetate was eliminated in the resultant strains. Additionally, 3-hydroxypropionic acid (3-HP) that is one of the most interest among alternative chemicals derived from biomass as precursor of acryl derivatives, could be produced from glycerol by the native and engineered strains of K. pneumoniae. The recombinant strains would be valuable as a platform strain for development of industrial process of production of 1,3-PD or 3-HP from glycerol.
저자
간행물 정보
발행기관
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- 발행기관명
- 한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
- 설립연도
- 1984
- 분야
- 공학>생물공학
- 소개
- 이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다 1. 생물공학 분야의 발전을 위한 연구 협력 2. 생물공학의 실용화를 촉진시키기 위한 산학 협동 3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최 4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간 5. 생물공학 발전을 위한 정책 건의 6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동
간행물
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- 간행물명
- 한국생물공학회 학술대회
- 간기
- 반년간
- 수록기간
- 1985~2013
- 십진분류
- KDC 476 DDC 576
이 권호 내 다른 논문 / 한국생물공학회 학술대회 2009 추계학술대회 및 국제심포지움
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