Young Ju Lee, Ka-Hwa Lee, Chang-Bum Ahn, Soon-Sil Chun, Jae-Young Je
언어
영어(ENG)
URL
https://www.earticle.net/Article/A114196
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원문정보
초록
영어
The objective of this study was to evaluate the antioxidant effects and acetylcholinesterase (AChE) inhibition activity of mulberry fruit extracts prepared by hot water (MFH) and 80% ethanol (MFE). Total polyphenolic contents of MFH and MFE were 195±3.4 mg gallic acid equivalents/g MFH and 185±2.8 mg gallic acid equivalents/g MFE. MFH and MFE significantly quenched 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide dose-dependently, and showed high chelating ability and reducing power in non-cellular systems. MFH and MFE also inhibited the formation of intracellular reactive oxygen species and lipid peroxidation, and elevated intracellular glutathione (GSH) levels in RAW264.7 cells. In addition, MFH and MFE also dose-dependently suppressed AChE activity.
목차
Abstract Introduction Materials and Methods Results and Discussion References