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Sesaminol Glucosides Improve Cognitive Deficits and Oxidative Stress in SAMP8 Mice

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 18 Number 6 (2009.12)바로가기
  • 페이지
    pp.1311-1315
  • 저자
    Min Young Um, Won Hee Choi, Ji Yun Ahn, Suna Kim, Mi Kyung Kim, Tae Youl Ha
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A114134

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원문정보

초록

영어
The objective of this study was to investigate the effects of sesaminol glucosides (SG) on age-related cognitive deficits in senescence-accelerated mice P8 (SAMP8). Male SAMP8 (9 month-old) were randomly divided into 3 groups and received diets containing 0, 0.25, or 0.5% SG for 12 weeks. Step-through latency of the SAMP8 control group was higher than that of the senescence-accelerated resistant mice (SAMR) group, whereas it was lowered in the SG-supplemented group on the passive-avoidance test. In the Morris water maze, the escape latency of the SAMP8 control group was increased and recovered in the 0.5% SG-supplemented group. The SG supplementation significantly decreased thiobarbituric acid reactive substance (TBARS) levels in brains of the SAMP8. On the other hand, catalase, superoxide dismutase, and glutathione peroxidase activities in brains of the SG supplemented group decreased compared with the SAMP8 control group. These results suggest that SG could attenuate cognitive deficits caused by aging through its antioxidant capacity.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

senescence-accelerated mice P8 aging cognitive deficit oxidative stress sesaminol glucoside

저자

  • Min Young Um [ Functional Food Technology Research Group, Korea Food Research Institute ]
  • Won Hee Choi [ Functional Food Technology Research Group, Korea Food Research Institute ]
  • Ji Yun Ahn [ Functional Food Technology Research Group, Korea Food Research Institute ]
  • Suna Kim [ Functional Food Technology Research Group, Korea Food Research Institute ]
  • Mi Kyung Kim [ Department of Nutritional Science and Food Management, College of Health Sciences, Ewha Womans University ]
  • Tae Youl Ha [ Functional Food Technology Research Group, Korea Food Research Institute ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 18 Number 6

    피인용수 : 0(자료제공 : 네이버학술정보)

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