Earticle

초록

영어

In this study, the anticancer activity of the water extract at 100oC was compared to that of the callus extracts via a ultrasonification extraction process. All the extracts were utilized to evaluate cytotoxicity, antioxidant and immune activities. The callus extracted via ultrasonification extraction showed relatively low cytotoxicity on normal human cell lines, HEK293 and HEL299, showing 13.17% and 21.78%, respectively. The callus extract has 59.82% which was similar to 61.70% for water extracts. It was also found that callus extract yielded higher nitric oxide secretion form macrophage than other extracts. The growths of both human stomach adenocarcinoma (AGS) cell and human lung carcinoma (A549) were inhibited up to 70% by adding 1.0 mg/mL of the callus extracts with ultrasonification extraction. This inhibition ratio (70%) was almost close to that of water extract. Human hepatoma carcinoma (HEP3B) cell growth was most significantly inhibited up to 75% by adding 1.0 mg/mL of callus extracts, and its selectivity was highest compared to other extracts. It indicates that the callus extracts could selectively inhibit growth of digestive system-related cancer cells. It can be also concluded from the results of this study that the callus extracts associated with ultrasonification extraction process have the potential for anticancer activity.

목차

Abstract
 서 론
 재료 및 방법
 결과 및 고찰
 요 약
 문 헌

키워드

저자

• 하지혜 [ Ji Hye Ha | 강원대학교 BT 특성화학부대학 ]
• 정향숙 [ Hyang Suk Jeong | 강원대학교 BT 특성화학부대학 ]
• 정명훈 [ Myoung Hoon Jeong | 강원대학교 BT 특성화학부대학 ]
• 김승섭 [ Seung Seop Kim | 강원대학교 BT 특성화학부대학 ]
• 김영 [ Ling Jin | 강원대학교 BT 특성화학부대학 ]
• 남종현 [ Jong Hyun Nam | (주)그래미 ]
• 황백 [ Baik Hwang | 전남대학교 생물학과 ]
• 마충제 [ Choong Je Ma | 강원대학교 BT 특성화학부대학 ]
• 이현용 [ Hyeon Yong Lee | 강원대학교 생명공학연구소 ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국식품과학회지 [Korean Journal of Food Science and Technology]

• 간기

  격월간

• pISSN

  0367-6293

• 수록기간

  1969~2011

• 십진분류

  KDC 574 DDC 664