Earticle

초록

영어

This study evaluated the effects of γ-irradiation on immunomodulating properties and structural changes of β-glucan. β- Glucan solutions (10 mg/mL) were γ-irradiated at 10, 30, and 50 kGy. Splenocyte proliferation and cytokine (interferon-γ and interlukin-2) productions by γ-irradiated β-glucan were evaluated in in vivo and in vitro, and structural changes of β-glucan were also determined after γ-irradiation. γ-Irradiation on β-glucan at 50 kGy enhanced splenocyte proliferation and cytokine productions, (p<0.05) and cleft glycosidic bonds of β-glucan resulting in lower the molecular weight. These results indicate that the use of γ- irradiation on β-glucan may be useful for improving its immunological activity by lowering the molecular weight of β-glucan.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

저자

• Jae-Hun Kim [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Nak-Yun Sung [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Eui-Hong Byun [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of BioScience & Biotechnology, Kyushu University ]
• Sun-Kyu Kwon [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Beom-Seok Song [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Jong-il Choi [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Yohan Yoon [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Jin-Kyu Kim [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Myung-Woo Byun [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ]
• Ju-Woon Lee [ Team for Radiation Food Science & Biotechnology, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute ] Corresponding Author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664