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Antioxidant and NO-scavenging Activities of Acanthopanax senticosus var. subinermis Leaf Extracts Prepared Using Ethanol and Extrusion Processing

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 18 Number 5 (2009.10)바로가기
  • 페이지
    pp.1124-1131
  • 저자
    Sung Hee Lee, Hea Young Oh, Jae Yoon Leem, Sun Yoon
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A112610

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원문정보

초록

영어
Acanthopanax senticosus has been used in East Asia as a traditional medicine. The purpose of this study is the investigation of an extraction method for A. senticosus var. subinermis (ASvS) leaves to improve their antioxidant and antiinflammatory activities. Six extracts were prepared: extracted with water (W), ethanol (Eth), water or ethanol after ultra high pressure (WP, EthP), and water or ethanol after an extrusion process (WEx, EthEx). Diphenylpicrylhydrazyl (DPPH) radical scavenging activity and ferric reducing ability showed that all extracts had a significant antioxidant activity. In anti-inflammatory activities, Eth and EthEx significantly inhibited the release of lipopolysaccharide (LPS)-induced nitric oxide (NO), tumor necrosis factor (TNF)-α, and interleukin (IL)-1β independent of cell viability in RAW 264.7 macrophage cells. Inducible NO synthase (iNOS) protein was significantly decreased by EthEx. These findings present that Eth and EthEx extracts of ASvS leaves have anti-inflammatory activities, and EthEx extract suppresses LPS-induced NO through the down-regulation of iNOS and proinflammatory cytokines.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

Acanthopanax senticosus var. subinermis antioxidant nitric oxide inducible nitric oxide synthase extrusion

저자

  • Sung Hee Lee [ Department of Food and Nutrition, Brain Korea 21 Project, Yonsei University, College of Human Ecology ]
  • Hea Young Oh [ Department of Food and Nutrition, Brain Korea 21 Project, Yonsei University, College of Human Ecology ]
  • Jae Yoon Leem [ Department of Phamacy, College of Pharmacy, Woosuk University ]
  • Sun Yoon [ Department of Food and Nutrition, Brain Korea 21 Project, Yonsei University, College of Human Ecology ] Corresponding Author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 18 Number 5

    피인용수 : 0(자료제공 : 네이버학술정보)

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