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Anti-inflammatory Activities of Ethylacetate Extract of Rehmannia glutinosa in LPS-induced RAW 264.7 Cells

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 18 Number 4 (2009.08)바로가기
  • 페이지
    pp.923-927
  • 저자
    Chang Hyun Jin, Min Ah Kang, Young Man Lee, Yong Dae Park, Dae Seong Choi, Myung Woo Byun, Il Yun Jeong
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A110368

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원문정보

초록

영어
This study is to investigate the anti-inflammatory effects of the ethylacetate extract of Rehmannia glutinosa(RGEAE). The anti-inflammatory activities using nitric oxide (NO), cytokine, and chemokine production in lipopolysaccharide(LPS)-induced RAW 264.7 cells were checked. Results indicated that RGEAE suppressed the NO, interleukin-6 (IL-6), andmonocyte chemoattractant protein-1 (MCP-1) production in a dose-dependent manner. Inhibition of NO formation was due to adecrease in inducible NOS (iNOS) expression. It was also found that the anti-inflammatory activities of RGEAE resulted from itsinhibitory role on the nuclear factor (NF)-κB activation and reactive oxygen species (ROS) production. Therefore, it is suggestedthat RGEAE has potential as a therapeutic material to attenuate the inflammatory disease such as rheumatoid arthritis.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

저자

  • Chang Hyun Jin [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ]
  • Young Man Lee [ Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756, Korea ]
  • Min Ah Kang [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ]
  • Yong Dae Park [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ]
  • Dae Seong Choi [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ]
  • Myung Woo Byun [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ]
  • Il Yun Jeong [ Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup, Jeonbuk 580-185, Korea ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

이 권호 내 다른 논문 / Food Science and Biotechnology Volume 18 Number 4

    피인용수 : 0건 (자료제공 : 네이버학술정보)

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