Earticle

초록

영어

The polysaccharide (BB-pol) extracted from Bifidobacterium bifidum BGN4 showed growth inhibitory effects onseveral colon cancer cell lines such as HT-29 and HCT-116. To increase the yield of polysaccharide, B. bifidum BGN4 wascultured in various culture media with different compositions. When B. bifidum BGN4 was cultured in modified MRS brothcontaining phytic acid, the cells showed increased branch formation and enlarged morphology. The content of totalcarbohydrate and the ability of adhesion to intestinal epithelial cells were also increased by phytic acid. The polysaccharideobtained from the cells grown in the presence of phytic acid inhibited the proliferation of cancer cell lines such as HT-29 andMCF-7 cells but not normal colon cell line, FHC. Taken together, Bifidobacterium grown in the presence of phytic acid mayconfer enhanced beneficial function for the host.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

저자

• Seockmo Ku [ Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul 151-742, Korea ]
• Hyun Ju You [ Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul 151-742, Korea ]
• Geun Eog Ji [ Department of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul 151-742, Korea; Research Center, Bifido, Inc., Hongcheon, Gangwon 250-804, Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664