Since conjugated linoleic acid (CLA) was identified as a principal anticancer component from ground beef in the1980s, CLA research has discovered that CLA has a wide range of biologically beneficial effects. Clinical studies with CLAare on the rise, and it is apparent that CLA may not be as effective in humans as in rodents, in particular its anti-obesity aspect.In addition, research with regard to other conjugated fatty acids as well as CLA metabolites is still in its infancy. Investigationof bioactivities for other conjugated fatty acids and CLA metabolites may help to extend the understanding of CLA and itsmechanisms of actions. This may pose an opportunity to use CLA more efficiently and expand the future use of otherconjugated fatty acids as pharmacological agents to assist current treatments.
목차
Abstract Introduction Origins of CLA Biological Activities of CLA CLA Isomer Interaction Safety Issues Other Conjugated Fatty Acids Conclusion References
키워드
conjugated linoleic acid (CLA)conjugated trans fatty acidobesitycardiovascular diseasescancerbone
저자
Yeonhwa Park [ Department of Food Science, University of Massachusetts, Amherst, 100 Holdsworth Way, Amherst, MA 01003, USA ]
Corresponding author
Michael W. Pariza [ Food Research Institute, University of Wisconsin-Madison, 1550 Linden Dr., Madison, WI 53706, USA ]