Earticle

초록

영어

Xanthorrhizol, a sesquiterpene isolated from Curcuma xanthorrhiza Roxb., was used to investigate its effect onreducing the saliva and multi-species oral biofilms consisting of Streptococcus mutans, Streptococcus sanguis, and Actinomycesviscosus by anti-biofilm and confocal laser scanning microscopy (CLSM) assays. Xanthorrhizol exhibited significant anti-biofilm activity in the dose- and time-dependent manners. Exposure to 2 and 5µg/mL xanthorrhizol for 30min remained<50% of saliva and multi-species biofilms formed for 24hr. In addition, exposure to 10µg/mL xanthorrhizol for 30minreduced 65 and 77% of 24hr saliva and multi-species oral biofilms, respectively. CLSM results visually demonstrated thatxanthorrhizol reduced bacterial viability in the saliva and multi-species oral biofilms. These results suggest that C.xanthorrhiza Roxb. containing xanthorrhizol with strong anti-biofilm activity can be employed as a plant source for oral carefunctional foods.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

저자

• Yanti [ Department of Biotechnology, Yonsei University, Seoul 120-749, Korea; Faculty of Biotechnology, Atma Jaya Catholic University, Jakarta 12930, Indonesia ]
• Yaya Rukayadi [ Department of Biotechnology, Yonsei University, Seoul 120-749, Korea; Research Center for Bioresources & Biotechnology, Bogor Agricultural University, Bogor 16880, Indonesia ]
• Kwanhyoung Lee [ Department of Biomaterials Science and Technology, Yonsei University, Seoul 120-749, Korea ]
• Sunghwa Han [ Department of Biomaterials Science and Technology, Yonsei University, Seoul 120-749, Korea ]
• Jae-Kwan Hwang [ Department of Biotechnology, Yonsei University, Seoul 120-749, Korea; Department of Biomaterials Science and Technology, Yonsei University, Seoul 120-749, Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664