Jin KIM, Du Bock KIM, Kyong-Hwan CHUNG, Ki-Young LEE, Dong-Woon KIM
언어
영어(ENG)
URL
https://www.earticle.net/Article/A105431
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원문정보
초록
영어
The aim of this work was to prepare liposome containing vancomycin and propolis for topical delivery.The vancomycin and propolis were successfully encapsulated in phosphatidyl choline-based liposomes and the possible improvement of their antioxidant and antimicrobial activities was tested against selected microbial. Particles with regular morphology, mean diameter ranging 100nm to 300nm, and good entrapment efficiency for propolis were obtained. The in vitro antimicrobial activity of nanoparticles was evaluated against microorganism of MRSA (Methicillin-resistant Staphylococcus aureus) and MRSE (Methicillin-resistant Staphylococcus epidermidis). The percentage of the encapsulated propolis and vancomycin was determined by uv-vis spectrophotometer. In order to investigate any possible synergistic or antagonistic effect between propolis and vancomycin, the antimicrobial activities of the mixtures, were also determined before and after encapsulation in liposomes. The antibiotics loaded liposomes can be used as a potential carrier for topical delivery.
키워드
vancomycinpropolisliposome
저자
Jin KIM [ Department of Advanced Chemicals Graduate School, Chonnam National University ]
Du Bock KIM [ Department of Advanced Chemicals Graduate School, Chonnam National University ]
Kyong-Hwan CHUNG [ Center for Functional Nano Fine Chemicals, Chonnam National University ]
Ki-Young LEE [ Center for Functional Nano Fine Chemicals, Chonnam National University ]
Dong-Woon KIM [ Deparment of Clinical Pathology, Gwangyang Health College ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동