Jin KIM, Hyo-Yun JUNG, Kyong-Hwan CHUNG, Ki-Young LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A105430
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원문정보
초록
영어
The objective of the present work was to develop a new drug nanocarrier consisting of nanoparticles made of glycol chitosan(Gc) and eicosapentaenoic acid (EPA). We describe EPA conjugated Gc self-assembled nanoparticles as a promising system for inhibit inflammation in keratinocytes. Gc-EPA formed self-assembled nanoparticles spherical shape and diameter of approximately 100 nm by probe sonication in aqueous medium. EPA was loaded in to the Gc-EPA nanoparticles as a model drug. The chracteristics of EPA loaded Gc-EPA nanoparticles was analyzed using DLS, TEM and DSC. Their size increased from 250-450nm. The in vivo release behavior of EPA from Gc-EPA nanoparticles was studied by a dialysis method in phosphate buffered saline. EPA loaded Gc-EPA nanoparticles are valuable to enhance the absorption of a poorly water soluble water.
키워드
Eicosapentaenoic acidglycol chitosannanocarrier
저자
Jin KIM [ Department of Advanced Chemicals Graduate School, Chonnam National University ]
Hyo-Yun JUNG [ Interdisciplinary Program of Perfume and Cosmetic, Chonnam National University ]
Kyong-Hwan CHUNG [ Center for Functional Nano Fine Chemicals, Chonnam National University ]
Ki-Young LEE [ Department of Applied Chemical Engineering & The Research Institute for Catalysis, Chonnam National University500-757, Korea ,. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동