We extracted by three ways and we was identified ROS scavenging activity in Aderium (complex plant extract: Euryale ferox, Hericium erinaceum, and Adenosphora triphylla).1; 2; 3) There are shaking using 70% ethanol, SCF (super critical fluid system), and fermentation using Lactobacillus helveticus KCTC 3545 in three ways of extraction. Fermented extract was most highly among the three in ROS scavenging activity. We know that if effective material is fermented, it is increased nutritive component and it is reduced particle size of component, therefore it is evaluated penetration of skin. On the base of above results, we tried safety test in vivo and in vitro, efficacy test measuring such as moisturizing, TEWL (transepidermal water loss) in vivo. It was applied 1 % of extract on cream base and there was no cytotoxicity in cell assay using fibroblast and patch test. Moisturizing and TEWL value was shown a reciprocal curve and we observed increase and decrease between fermented Aderium (treatment) and non-fermented Aderium (control) at 8 h. Treat part was superior 23 % of moisturizing value compare with control and TEWL value was lower than control (16 %). Hereby, we defined valuable activity in fermented Aderium. We will measure elasticity in vivo and will analyze main potential materials and then we will apply to commercial cosmetics product as new raw materials.
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동