Earticle

초록

영어

Phytochemical researches on Glycyrrhiza uralensis root have revealed the existence of abundant polyphenol glycosides such as liquiritin and liquiritin apioside. On the basis of earlier reported researches, we could expect that Glycyrrhiza uralensis root is a medicinal herb useful for polyphenol preparation as well as its polyphenol glycosides will be converted to the corresponding aglycones, which have more active form in skin biology, by employing Nuruk fermentation. As expected, HPLC results revealed that the polyphenol glycosides obviously
underwent deglycosidation reaction during Nuruk fermentation, thereby indicating that Aspergillus niger and Aspergillus oryzae, major fungi in Nuruk, are very effective in bioconverting vegetable polyphenol glycosides to alycones. As such results, increase of liquiritigenin peak was evidently observed together with simultaneous decrease of each two peak corresponding to liquritin and liquiritin apioside. The conversion rate was more than 95% and the chemical structure of
liquiritigenin was confirmed by NMR analysis. These results indicated that Nuruk fermentation is a good method to prepare in high yield liquiritigenin, an estrogenic substrate. Koji acid, a direct tyrosinase deactivator, was also identified by HPLC analysis. Thus, the final Nuruk ferment will function skin whitening and wrinkle prevention. Like this, combining two or more agents via different active mechanisms in a raw material for cosmetics preparation will contribute to further
improvement of skin beauty.

키워드

저자

• Byung-Jhip HA [ Biomaterial Research Team, Cotde Inc., ]
• Chang-Sub KU [ Biomaterial Research Team, Cotde Inc., ]
• Dong-Jun BAE [ Biomaterial Research Team, Cotde Inc., ]
• Kyu-Sang HWANG [ Biomaterial Research Team, Cotde Inc., ]
• Chang-Ho KIM [ Biomaterial Research Team, Cotde Inc., ]
• Dong-IL JANG [ Biomaterial Research Team, Cotde Inc., ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576