Onion is a term used for many plants in the genus Allium. They are known by the common name "onion" but, it usually refers to Allium cepa (A. cepa). A. cepa is also known as the ‘garden onion’ or ‘bulb’ onion and ‘shallot’. The purpose of this study was to investigate the effect of A. cepa extracts on hair growth in an alopecia model of C57BL/6N mice. First, antioxidative activities of A. cepa extracts were examined with the stable free radical diphenylpicryl-hydrazyl (DPPH) scavenging activity and the total polyphenol content. The amount of quercetin in A. cepa extracts was examined by the inductively coupled plasma mass spectroscopy (ICP/MS). For animal test, mice were randomized and separated into six experimental groups including 50% ethanol (negative control), minoxidill, Acorus calamus extract, fresh onion juice, ethanol extract of A. cepa and hot water extract of A. cepa. Quercetin was detected in A. cepa juice to be 47.49 ppm but not detected in other fractions. The hair-promoting activity appeared in the fraction without quercetin. This result suggested that the famous polyphenol quercetin showed no relation with hair growth so other compounds should be investigated afterwards.
키워드
Allim cepaHair growthmouse model
저자
Heang Hee JOO [ Dept. Beauty & Cosmietics, Graduate School of Industry, Chosun University ]
Se Hwan KWON [ Dept. Chem. & Biochem. Eng., School of Engineering, Chosun University, Gwangju. ]
Hyun-Jae SHIN [ Dept. Chem. & Biochem. Eng., School of Engineering, Chosun University, Gwangju. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동