Earticle

초록

영어

Poly (2-hydroxyethyl methacrylate) (pHEMA) is a common synthetic, hydrogel material that is frequently used as a biomaterial due to their high water content, non-toxicity and favorable tissue compatibility, which leads to many applications such as bio-compatible materials including soft contact lenses, kidney dialysis systems, drug-delivery systems and artificial lever support systems. Because of hydrophilic material`s poor interface cells, cell adhesion was weaker on pHEMA, as a significant fraction of the fibroblasts revealed a lack of spreading, with most cells remaining spherical. However, cell adhesion on pHEMA is needed for versatile bio-applications. In this work, GPTMS was used for surface modification of pHEMA to have epoxy groups
exposed on the surface of the material. The coupling reaction was happened between methoxy groups of GPTMS and hydroxyl groups of pHEMA. The characteristic of epoxy group that helps cell adhesion on the surface of pHEMA could be suitable to measure of intensity depended on various concentration of protein. Therefore, it can be applied to detect protein as a bio-sensor.

키워드

저자

• Seung Hee NAM [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Yoel LEE [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Dae Nyun KIM [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Sang Phil PARK [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Eunji JANG [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Seami PARK [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Hyun Jong LEE [ Department of Chemical and biomolecular Engineering, Yonsei University. ]
• Won-Gun KOH [ Department of Chemical and biomolecular Engineering, Yonsei University. ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576