Sun-Mi LEE, Min-Ok CHO, S. PARK, Youngsoon UM, Byoung-In SANG
언어
영어(ENG)
URL
https://www.earticle.net/Article/A105262
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원문정보
초록
영어
Solventogenic clostridia lose their ability to produce solvent during repeated sub-culturing of batch culture or during a continuous fermentation. This phenomenon is known as 'degeneration' and degeneration of solventogenic clostridia causes failure of stable butanol production during continuous fermentation. Therefore it is needed to prevent the degeneration of cells and maintain the cells in solventogenic phase. In this study, we investigated the quorum sensing signal in Clostidium acetobutylicum during biobutanol production and the relationships between the phenomenon of degeneration and the quorum sensing signal. By measuring the activity of autoinducer-2 (AI-2), a quorum sensing signal molecule, we found out that solventogenic C. acetobutylicum produces AI-2. However, degenerated C. acetobutylicum did not seem to produce AI-2 during their cell cycles. In addition, the effects of quorum sensing signal molecule analogs to biobutanol production were investigated during batch fermentation of C. acetobutylicum.
키워드
quorum sensingdegenerationSolventogenic clostridia
저자
Sun-Mi LEE [ Korea Institute of Science and Technology. ]
Min-Ok CHO [ Korea Institute of Science and Technology. ]
S. PARK [ Ewha Womans University. ]
Youngsoon UM [ Korea Institute of Science and Technology ]
Byoung-In SANG [ Korea Institute of Science and Technology ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동