Earticle

초록

영어

Lysimachia foenum-graecum Hance., a herbal species grown in China, is mainly treated as a spice, insectifuge, and medicinal plant and the dried aerial parts have been traditionally used for the treatment of rheum, headache, toothache, and the diseases of the digestive system. Reactive oxygen species, such as O2.¯, H2O2, and ·OH, mediate reactions which can result in the damage of critical biological molecules including DNA and cellular protein. In this study, extracts of Lysimachia foenum-graecum Hance. With were ethanol, methanol, hot-water found to contain biological and pharmacological activities that may contribute to chemopreventive effects. antioxidant activities by hot-water extracts from Lysimachia foenum-graecum Hance. were investigated in vitro. Various methods, for the radical-scavenging activities of the ethanol, methanol, and hot-water extracts were examined by using α,α-diphenyl-β-picrylhydrazyl (DPPH) radicals and 2,2'-azino-bis(3-ethylbenzthiazoline- 6-sulfonic acid) (ABTS) assay. After cell viability was measured to decide the proper sample concentration, no cytotoxicity was shown in RAW 264.7 cell line using MTT assay and 2', 7'-Dichlorodihydrofluorescein diacetate(DCFDA)assay.

키워드

저자

• Jung Woon PAHK [ Dept. of Bioengineering and Technology, Kangwon National University, ]
• Eock Kee HONG [ Dept. of Bioengineering and Technology, Kangwon National University, ]

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  한국생물공학회 학술대회

• 간기

  반년간

• 수록기간

  1985~2013

• 십진분류

  KDC 476 DDC 576