Tae Woo LEE, Jong Myoung PARK, Tae Yong KIM, Sang Yup LEE
언어
영어(ENG)
URL
https://www.earticle.net/Article/A104847
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
The advent of in silico genome-scale model developed various algorithms for the gene targeting. Flux balance analysis (FBA) optimizes a specific objective function by linear programming under pseudo-steady state based on the stoichiometry of metabolic reactions. . However, single objective algorithms optimize only the limited objective function. To improve a strain for biochemical production, the organism should be investigated from diverse sides simultaneously: for instance, biomass formation, biochemical production, and waste formation In this respect, we propose a new approach called the flux scanning with compromised objective fluxes (FSCOF), multi-objective algorithm. [This work was supported by Korean Systems Biology Research program (M10309020000-03B5002-00000) of the Ministry of Education, Science and Technology. Further supports by LG Chem Chair Professorship, Microsoft and IBM SUR program are appreciated.]
키워드
in silicoFlux balance analysis (FBA)flux scanning with compromised objective fluxes (FSCOF)
저자
Tae Woo LEE [ Department of Chemical & Biomolecular Engineering(BK21 program), KAIST, Daejeon 305-701. ]
Jong Myoung PARK [ Department of Chemical & Biomolecular Engineering(BK21 program), KAIST, Daejeon 305-701. ]
Tae Yong KIM [ Department of Chemical & Biomolecular Engineering(BK21 program), KAIST, Daejeon 305-701. ]
Sang Yup LEE [ Department of Chemical & Biomolecular Engineering(BK21 program), KAIST, Daejeon 305-701. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동