Synthetic biology is an emerging field that aims to design and build synthetic networks of biological reactions using well-characterized biomolecular components and genetic modules. While the current efforts in synthetic biology rely mostly on the engineering of living host cells, progress in the in vitro synthesis of DNA, RNA or proteins make it possible to construct truly 'synthetic' networks of biological functions. In particular, recent advances in the techniques of cell-free protein synthesis are expected to provide a versatile platform for the in situ construction of in vitro networks of important proteins. Compared to in vivo synthetic biology, in vitro synthetic biology offers substantial advantages including increased flexibility of engineering and less background interference with the synthetic enzyme network. Herewith, we present and discuss our recent achievements in the development of cell-free protein synthesis systems, which have been modified in various configurations to allow the flexible manipulation of gene expression and reaction conditions. We expect that the developed systems will be used for studying focused and intentional regulation of protein synthesis and other biological functions in the context of synthetic biology.
저자
Dong-Myung Kim [ Department of Fine Chemical Engineering and Chemistry, Chungnam National University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동