MYOUNGJOO PARK, YOICHIROU MATUO, YOKO AKIYAMA, YOSHINOBU IZUMI, SHIGEHIRO NISHIJIMA
언어
영어(ENG)
URL
https://www.earticle.net/Article/A104406
원문정보
초록
영어
The effect of low doses of ultraviolet (UV) irradiation on morphology changes of cell has been studied based on the observation of the cell length. It was shown that UV-irradiated cell has different behavior in comparison with nonirradiated cell. From the histogram of cell-length distribution, it was confirmed that cell cycle of non irradiated cell was 28 hours, and that cell cycle of irradiated cell with dose of 20 Jm-2 was delayed (39 hours), while irradiated cell with 40 Jm-2 and 60 Jm-2 did not divide and kept growing continuously. It was supposed that in case of 20 Jm-2 of irradiation dose, the cell cycle was delayed because the checkpoint worked in order to repair DNA damage induced by generation of pyrimidine dimer, reactive oxygen species and so on. It was also supposed that in case of 40 Jm-2 and 60 Jm-2 of irradiation dose, overgrowth was induced because the checkpoint was not worked well. The morphology of overgrown cell was similar to that of normally senescent cell. Therefore, it was considered that cell senescence was accelerated by UV irradiation with irradiation doses of 40 Jm-2 and 60 Jm-2.
목차
1. INTRODUCTION 2. MATERIALS AND METHODS 2.1 Cell Sample 2.2 Cell Cycle Synchronization 2.3. Effect of UVC Irradiation on ADSCs 3. RESULTS 3.1 Synchronization of Cell Cycle by Serum Starvation 3.2 The Effect of UVC Irradiation on ADSCs 4. DISCUSSION 5. CONCLUSION REFERENCES
대한방사선방어학회 [Korean Association For Radiation Protection]
설립연도
1975
분야
자연과학>기타자연과학
소개
회원 상호간의 협조와 친목을 도모함으로써 방사선방어에 관한 제반연구 및 발전에 이바지함을 물론 학술의 국제교류 및 국제학술단체와의 상호협력 증진에 기여함을 목적으로 하며, 이 목적을 달성하기 위하여 다음 각 호의 사업을 한다.
1. 방사선방어에 관한 학술연구발표회 및 강연회 등의 개최
2. 학회지 및 방사선방어에 관한 학술간행물의 발행 및 배포
3. 방사선방어에 관한 학술의 국제교류 및 협력
4. 방사선방어에 관한 국제학술자료의 조사, 수집 및 번역
5. 방사선방어에 관한 조사 및 연구용역
6. 회원의 연구활동을 위한 제반협조
7. 기타 본 학회의 목적 달성에 필요한 사항
간행물
간행물명
방사선방어학회지 [Journal of Radiation Protection and Research]