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Influence of Long-term Supplementation with Korean Red Ginseng on in vivo Antioxidant Capacities in Rats

첫 페이지 보기
  • 발행기관
    한국식품과학회 바로가기
  • 간행물
    Food Science and Biotechnology SCIE KCI 등재 SCOPUS 바로가기
  • 통권
    Volume 18 Number 1 (2009.02)바로가기
  • 페이지
    pp.234-238
  • 저자
    Heung-Bin Lim, Dong-Wook Lee, Junsoo Lee
  • 언어
    영어(ENG)
  • URL
    https://www.earticle.net/Article/A103108

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원문정보

초록

영어
Effects of ginseng on in vivo antioxidant capacities with age were studied in rats. All rats were reared in theconventional system. Ginseng-treated rats were supplied with ginseng water extracts (25mg/kg/day) continuously from 6weeks of age to spontaneous death. None of the rats showed any discernible adverse effects of treatment with ginseng-containing water. There was no significant difference in body weight (BW) gains with age between treated and control groups.However, ginseng extracts did cause a decrease in the level of serum low density lipoprotein (LDL)-cholesterol, glucose, andthiobarbituric acid reactive substances (TBARS) in the treated rats. The activities of superoxide dismutase (SOD), catalase,and glutathione peroxidase in liver cytosol decreased with age in the control group. However, these enzyme activities werewell maintained in the ginseng-treated rats and, especially, catalase and glutathione peroxidase activities were consistentlyhigher than in control rats. The levels of total sulfhydryl group (T-SH) and glutathione reductase (GR) were unchanged, andglutathione-S-transferase (GST) activity gradually decreased with age in both groups. There were no differences in T-SH, GR,or GST between the control and treatment groups. These results indicate that long-term administration of ginseng retards age-related deterioration in some biochemical parameters such as cholesterol, glucose, and lactate dehydrogenase in serum and ithas an enhancing effect on antioxidant capacity in the liver.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

Korean red ginseng antioxidant enzyme long-term supplementation

저자

  • Heung-Bin Lim [ Department of Industrial Plant Science and Technology, Chungbuk National University, Cheongju, Chungbuk 361-763, Korea ]
  • Dong-Wook Lee [ Laboratory of Biochemistry, KT&G Central Research Institute, Daejeon 305-345, Korea ]
  • Junsoo Lee [ Department of Food Science and Technology, Chungbuk National University, Cheongju, Chungbuk 361-763, Korea ] Corresponding author

참고문헌

자료제공 : 네이버학술정보

간행물 정보

발행기관

  • 발행기관명
    한국식품과학회 [Korean Society of Food Science and Technology]
  • 설립연도
    1970
  • 분야
    농수해양>식품과학
  • 소개
    본회는 사회일반의이익에 공여하기 위하여 공공법인의 운영에 관한 법률의 규정에 따라 식품 과학 전반에 관한 이론 및 기술연구와 그 응용을 촉진 및 보급시키며 학술과 사업을 연계시키고, 나아가 국민의 식생활을 질적, 양적으로 향상시킴을 목적으로 한다.

간행물

  • 간행물명
    Food Science and Biotechnology
  • 간기
    격월간
  • pISSN
    1226-7708
  • 수록기간
    1992~2009
  • 십진분류
    KDC 574 DDC 664

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