Earticle

초록

영어

The aim of this study was to investigate effects of onion, red onion, or quercetin on plasma antioxidant vitamin,lipid peroxidation, and leukocyte DNA damage in rats fed a high fat-cholesterol diet. Forty SD male rats were assigned tonormal control, high fat-cholesterol diet (HF), or HF+5% onion powder, HF+5% red onion powder, or HF+0.01% quercetin.The HF diet resulted in significantly higher plasma lipid peroxidation which decreased with onion, red onion, or quercetinsupplementation. Leukocyte DNA damage induced by HF diet decreased significantly in rats fed onion and red onion, whilequercetin supplementation had no effect on preventing leukocyte DNA damage. H2O2 induced leukocyte DNA damageexhibited a highly significant negative correlation with plasma retinol and tocopherols. These results suggest that onion or redonion powder exerts a protective effect with regard to DNA damage in rats fed HF diet. However, 0.01% quercetin in pureform might not be effective at preventing DNA damage.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

키워드

저자

• Jae-Hee Park [ Department of Food and Nutrition, Kyungnam University, Masan, Gyeongnam 631-701, Korea ]
• Bo-Young Seo [ Department of Food and Nutrition, Kyungnam University, Masan, Gyeongnam 631-701, Korea ]
• Kyung-Hea Lee [ Department of Food and Nutrition, Changwon National University, Changwon, Gyeongnam 641-773, Korea ]
• Eunju Park [ Department of Food and Nutrition, Kyungnam University, Masan, Gyeongnam 631-701, Korea ] Corresponding author

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  Food Science and Biotechnology

• 간기

  격월간

• pISSN

  1226-7708

• 수록기간

  1992~2009

• 십진분류

  KDC 574 DDC 664