Earticle

초록

영어

Anorexia nervosa is one of severe neuropsychiatric disorders and appears more rate of incidence in therecent decade. Anorexia nervosa is also associated with abnormalities in neuroendocrine function. The hippocampus isthought to control learning and memory. It is also known that the hippocampus regulates eating behavior. The anorexiamutant mice (anx/anx) appear an autosomal recessive mode of inheritance and present phenotypically with decreasedfood intake and body weights compared to their wild-type littermates. However, the role of c-Jun in the hippocampusof anorexia mutant mice is still unclear. Therefore, to study the changes of c-Jun expression in the hippocampus ofanorexia mutant mice, the immunohistochemistry method was performed. Here we report that anorexia mutant miceshowed the decreased expression of c-Jun positive neurons in the dentate gyrus compared to the control mice, while thec-Jun expression of CA1 and CA2&3 were higher than that of the control mice, respectively.

목차

ABSTRACT
 1. Introduction
 2. Materials and methods
  2.1 Animals
  2.2 Materials
  2.3 Immunohistochemistry
  2.4 Statistical analyses
 3. Results and discussion
 References

키워드

저자

• Kwang Jae Lee [ Kohwang Medical Research Institute, School of Medicine, Kyung Hee University, Seoul 130-701, Korea ]
• Yong Ho Kim [ Department of Surgery, School of Medicine, Kyung Hee University, Seoul 130-701, Korea ]
• Bum Shik Kim [ Department of Thoracic and Cardiovascular Surgery, School of Medicine, Kyung Hee University, Seoul 130-701, Korea ]
• Joo Ho Chung [ Kohwang Medical Research Institute, School of Medicine, Kyung Hee University, Seoul 130-701, Korea ] 교신저자

참고문헌

발행기관

간행물

표지보기 관심저널 등록

• 간행물명

  응용미약자기에너지학회지 [Journal of Applied Micromagnetic Energy]

• 간기

  반년간

• pISSN

  1738-4427

• 수록기간

  2003~2018

• 십진분류

  KDC 428 DDC 538