Song-Eun LEE, Hong Soon RHEE, Seok Young SON, Hwa-Young CHO, Jong Moon PARK
언어
영어(ENG)
URL
https://www.earticle.net/Article/A100327
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원문정보
초록
영어
Eschscholtzia californica has been known as one of a traditional medicinal plant1) and shown to contain benzo[c]phenanthridine alkaloid used in the treatment of dental plaque and gingivitis.2) Among culture medium composition, nitrogen which exists in inorganic form, such as nitrate or ammonium in culture medium strongly influences on cell growth and secondary metabolites production. In this study, the effect of nitrogen source on cell growth and benzo[c]phenanthridine alkaloids production in suspension culture of Eschscholtzia californica were investigated. Experiments were conducted by modifying NH4 +/NO3 - ratio and total amount of initial nitrogen concentration in Murashige & Skoog (MS) medium. The increase of NH4 +/NO3 - ratio at total nitrogen concentration of 60mM caused decrease on cell growth and alkaloids production. Total amount of initial nitrogen concentration also had influence on cell growth and benzo[c]phenanthridine alkaloids production. From this result, we found that ammonium inhibited cell growth and benzo[c]phenanthridine alkaloids production and then we conducted further study to verify ammonium function.
저자
Song-Eun LEE [ Advanced Environmental Biotechnology Research Center, Dept. Chem. Eng. ]
Hong Soon RHEE [ Advanced Environmental Biotechnology Research Center, Dept. Chem. Eng. ]
Seok Young SON [ Advanced Environmental Biotechnology Research Center, Dept. Chem. Eng. ]
Hwa-Young CHO [ School of Environmental Science and Engineering, POSTECH ]
Jong Moon PARK [ Advanced Environmental Biotechnology Research Center, Dept. Chem. Eng. ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동