Seung-Ah Park, Jun-Seop Shin, Mi-Ryung Kim, Chan-Wha Kim
언어
영어(ENG)
URL
https://www.earticle.net/Article/A100091
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원문정보
초록
영어
Adipogenic differentiation needs many factors to regulate protein or RNA expression. Among them, factor to regulate extracelluar matrix were confirmed, which is expected to affect adipogenic differentiation. The protein profiles from the adipocytes differentiated from hMSC were determined by 2-D gel electrophoresis (2-DE), and the differentially expressed proteins were identified by MALDI-TOF and ESI-Q-TOF MS/MS analysis. Among these, the three up-regulated proteins (Calgizzarin, Kallikrein-9, and Ubiquitin) were newly identified from differentiated hMSC, which might prove to be useful biomarkers for the differentiation of hMSC into adipocytes. Over expression of Kallikrein-9 was reconfirmed in adipogenic cells by RT-PCR, Western blotting. This protein was expected to play important roles for adipogenic-differentiation which will be able to help understanding of differentiation related in its extracellular matrix (ECM) not in signal transduction
저자
Seung-Ah Park [ School of Life Sciences and Biotechnology, Korea University ]
Jun-Seop Shin [ School of Life Sciences and Biotechnology, Korea University ]
Mi-Ryung Kim [ School of Life Sciences and Biotechnology, Korea University ]
Chan-Wha Kim [ School of Life Sciences and Biotechnology, Korea University, ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동