Bio capsule molecule, Liposome was prepared by film dispersion method. Skin whitening agent, ‘Arbutin’ was dissolved in water before liposome formation and capsulated by liposome. Sonication and extrusion method were applied for the homogenization of the size and shape of liposome. Changes of liposome size and entrapment efficiency were investigated to confirm liposome stability.1) Arbutin encapsulation was also induced by size extrusion. Extrusion of liposome suspension was serially executed 400, 200, 100nm pore size membrane filter. Arbutin capsulated liposome was separated by superdex-100 column chromatography.2) Then, HPLC analysis was performed to report Entrapment efficiency of arbutin. Entrapment efficiency of pre-dissolved and extursion method were compared.
저자
Nam Hyuck Kim [ Department of Molecular Science and Technology, Ajou University ]
Sang Yo Byun [ Department of Molecular Science and Technology, Ajou University, ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동