Young-Soo Park, Jin-Il Kim, Long Van Duc Nquyen, Ju Weon Lee, Jeung Kun Kim, Si Wouk Kim, Yoon-Mo Koo
언어
영어(ENG)
URL
https://www.earticle.net/Article/A100052
※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.
원문정보
초록
영어
Natural indigo dye is the earliest dye obtained from leaves of plants. Various chemical synthesis methods for indigo dye had been reported. Using the chemical synthesis, indigo is produced with higher productivity and simpler process than obtainment from leaves of plants. The chemical synthesis of indigo, however, makes toxic materials which make pollution and bad effect on the human health. The indigo fermentation using microorganism has good characteristics to overcome the aforementioned problems of chemical synthesis and obtainment from plants. While indigo dye is produced by cell cultivation, indirubin is produced as one of byproducts. Indirubin and its derivatives are the inhibitor of cyclin dependent kinase (CDK) which participates in cell differentiation. Therefore, many studies to investigate the virtue of indirubin as the anticancer drug are performed. Before the purification of indirubin by using chromatography, a pretreatment step for crude indigo dye is necessary. Due to the low solubility of indigo and indirubin in water, several organic solvents were tested for selective batch extraction of indirubin from crude indigo dye. For efficient extraction, extraction process was developed by continuous operation.
저자
Young-Soo Park [ Department of Biological Engineering, Inha University ]
Jin-Il Kim [ Department of Biological Engineering, Inha University ]
Long Van Duc Nquyen [ Department of Biological Engineering, Inha University ]
Ju Weon Lee [ ERC for Advanced Bioseparation Technology, Inha University ]
Jeung Kun Kim [ ERC for Advanced Bioseparation Technology, Inha University ]
Si Wouk Kim [ Department of Environmental Engineering,, Chosun University ]
Yoon-Mo Koo [ Department of Biological Engineering, Inha University, ERC for Advanced Bioseparation Technology, Inha University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동