Na-Mi Park, Hye-Mee Park, Woo-Jin Chang, Yoon-Mo Koo
언어
영어(ENG)
URL
https://www.earticle.net/Article/A100015
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원문정보
초록
영어
Polyethylene glycol (PEG) conjugated biomolecules, such as proteins, antibody fragments, aptamers, peptides, and other small molecules, are widely used, because PEG can increase the solubility and stability of conjugated biomolecules in general. The chemical attachment of PEG to these biomolecules is referred to as “PEGylation". Various PEGylation techniques are well established so far, especially the reaction conditions, desired site and degree of PEGylation, etc. In this study, phase-separation properties of PEG or PEGylated IgG with dextran solution was compared. PEG (M.W. 10000) or PEGylated (M.W. 10000) mouse anti-human IgG was used with dextran T500 (10%, w/w) solution. The volume ratio of two phases in microchannel was compared based upon the infused volumetric flow rate of each polymer solution. Developed technique will be used for the simultaneous phase-separation and affinity separation of biomolecues.
저자
Na-Mi Park [ Department of Biological Engineering ]
Hye-Mee Park [ Department of Biological Engineering ]
Woo-Jin Chang [ ERC for Advanced Bioseparation Technology, Inha University ]
Yoon-Mo Koo [ Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University ]
한국생물공학회 [The Korean Society for Biotechnology and Bioengineering]
설립연도
1984
분야
공학>생물공학
소개
이 법인은 생물 공학의 발전과 보급에 이바지하고, 회원 상호 간의 연구 협력과 친목을 도모함을 목적으로 한다
1. 생물공학 분야의 발전을 위한 연구 협력
2. 생물공학의 실용화를 촉진시키기 위한 산학 협동
3. 학술연구 발표회, 강연회, 연수회 등 학술활동의 개최
4. 국,영문 학술지,소식지,학술회의 Proceedings 및 학술도서의 발간
5. 생물공학 발전을 위한 정책 건의
6. 기타 국제 교류 등 본 학회의 목적 달성을 위한 제반 활동