Earticle

초록

영어

This study was carried out to evaluate potential of Hypsizygus marmoreus (brown cultivar) as a functional food and drug materials. H. marmoreus were divided into pileus and stipe and extracted in hot water and 80% ethanol. The total polyphenol content was highest in the hot water extracts (pileus 17.15±0.19 mg of GAE g, stipe 7.37±0.16 mg of GAE/g) and pileus compared to the ethanol extracts (pileus 10.23±0.14 mg of GAE/g, stipe 3.76.±0.19 mg of GAE/g) and stipe. Also, hot water extracts of pileus from H. marmoreus (brown cultivar) was more effective DPPH, ABTS, ORAC value, reducing power than ethanol extracts and stipe extracts. The pileus and stipe extracts were confirmed to be non-cytotoxic in the mouse macrophage cell line RAW 264.7 determined by WST-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulphonate) assay. Overall, extracts of H. marmoreus (brown cultivar) was higher antioxidant activity than other mushrooms, and no cytotoxicity. Therefore, H. marmoreus (brown cultivar) showed potential as a functional food and drug materials. The brown cultivar of H. marmoreus have higher antioxidant activity than white cultivar, H. marmoreus seem to have different antioxidant activity depending on the cultivar.

목차

ABSTRACT
서론
재료 및 방법
느티만가닥버섯 추출물의 제조
총 폴리페놀 함량 측정
DPPH 라디칼 소거 활성
ABTS 라디칼 소거 활성
Oxygen radical absorbance capacity (ORAC) 측정
환원력(Reducing power) 측정
세포 생존율 측정
통계처리
결과 및 고찰
갈색 느티만가닥버섯 추출물의 총 폴리페놀 함량
갈색 느티만가닥버섯 추출물의 DPPH 라디칼 소거 활성
갈색 느티만가닥버섯 추출물의 ABTS 라디칼 소거 활성
갈색 느티만가닥버섯 추출물의 Oxygenradical absorbancecapacity(ORAC)
갈색 느티만가닥버섯 추출물의 환원력(Reducing power)측정
갈색 느티만가닥버섯 추출물이 대식세포 RAW 264.7의 세포생존율에 미치는 영향
적요
감사의 글
REFERENCES

저자

• 박민정 [ Min Jeong Park | 경상국립대학교 제약공학과 ]
• 유찬열 [ Chan Yeol Yu | 경남산림환경연구원 ]
• 조수정 [ Soo Jeong Cho | 경상국립대학교 제약공학과 ] Corresponding Author

참고문헌