Earticle

초록

영어

Samples (10 mg/mL) of wild Grifola frondosa aqueous extract and solvent fractions were examined for fibrinolytic, thrombin inhibitory, acetylcholinesterase inhibitory, and antioxidative activities to determine the biological activities. The fibrinolytic activity of the aqueous extract and solvent fractions was 0.93 and 0.73 plasmin units/mL, respectively. The thrombin inhibitory activity of the butanol extract was 79.60%. The chloroform fraction had high acetylcholinesterase inhibitory activity (85.88%). The aqueous extract had low antioxidative activity (39.81%). The aqueous fraction hydrolyzed Bβ subunits of human fibrinogen but did not show any reactivity for the γ form of the human fibrinogen. The findings indicate the potential of wild Grifola frondosa for the development of drugs and bio-functional foods to prevent cardiovascular diseases.

목차

ABSTRACT
서 론
재료 및 방법
실험재료
물 추출물과 유기용매 분획물 조제
혈전용해활성 측정
혈전용해효소에 의한 섬유소원의 분해 양상
트롬빈 저해활성 측정
Acetylcholinesterase(AchE) 저해 활성
전자공여능 측정
통계 분석
결과 및 고찰
용매별 분획물의 수율
혈전용해활성
혈전용해효소에 의한 섬유소원의 분해 양상
트롬빈 저해활성
Acetylcholinesterase 저해활성
항산화효과
적 요
REFERENCES

저자

• 석순자 [ Soon-Ja Seok | 단국대학교 미생물학과 ]
• 김준호 [ Jun-Ho Kim | 상지대학교 정밀화학신소재학과 ] Corresponding author

참고문헌